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  • Load image into Gallery viewer, Acebutolol
  • Load image into Gallery viewer, Acebutolol


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What is this medication? 

SECTRAL (Acebutolol)
Antihypertensive/Antiarrhythmic Class II Agent; Beta 1 Selective Blocker

Acebutolol is officially indicated for the treatment of hypertension, and ventricular premature beats.  It may also be prescribed off-label for thyrotoxicosis and stable ischemic heart disease.

How does this medication work? 

Beta 1 receptor is activated by adrenaline and is involved with cardiac output by increasing the volume of each pump as well as increasing the heart rate.  Acebutolol, Sectral works by blocking this receptor having the reverse effect thereby reducing heart rate and stroke volume.  At exceptionally high dosages it may start to affect Beta 2 receptors.

How should I take this medication? 

Oral: Start at 200-400mg daily in one or two divided doses then titrate up based on patient response/tolerance to a maximum of 1200mg/day.

How to Take: Follow instructions provided by physician/pharmacy label, take consistently at same times each day unless otherwise directed. 

You Need to Avoid: Careful standing up too quickly as you may get dizzy
Do not stop this medication abruptly to avoid rebound tachycardia, hypertension and in severe cases angina, heart attack, or arrhythmia.

What should I watch for while using this medication? 

Before starting Acebutolol, make sure your physician is aware of any allergies or medications you currently take, if you have a low resting heart rate, asthma or other bronchospastic disease, cardiac conduction abnormalities, diabetes, liver disease, myasthenia gravis, peripheral vascular disease, hyperthyroidism, or if pregnant/breastfeeding.

What if I miss a dose?

If you miss a dose of medication, try to take it as soon as possible. However, if it is almost time for your next dose, take only that scheduled dose. Do not take double or extra doses.

How should I store this medication?

Keep out of the reach of children at all times. Store at room temperature, 59 to 86° F (15 to 30° C). Protect from light. Keep the container tightly closed. Properly dispose of any unused medication after the expiration date.

What are the possible side effects of using this medication? 

Fatigue, headache, dizziness.

Note this is not a complete list of side effects for SECTRAL (Acebutolol), only common ones.