ALECENSA/ALECENSARO (Alectinib)

ALECENSA/ALECENSARO (Alectinib)

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HOFFMAN-LA ROCHE
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$11,989.99 USD
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prescription

What is this medication? 

ALECENSA/ALECENSARO (Alectinib)
Antineoplastic Agent

Brand Name US: Alecensa
Canadian Equivalent: Alecensaro

ALECENSA/ALECENSARO (Alectinib) is indicated for the treatment of metastatic non-small cell lung cancer.

How does this medication work?

Alectinib is a tyrosine kinase inhibitor that blocks the activity of anaplastic lymphoma kinase (ALK) on cancer cells.  Alectinib’s inhibition of ALK slows down and/or stops the growth of tumors.

How should I take this medication? 

Oral: Take 600mg twice daily; continue until disease progression or unacceptable toxicity.

How to Take:  Take with food.  Swallow the capsule whole; do not open or dissolve the contents of the capsule. 

What should I watch for while using this medication? 

ALECENSA/ALECENSARO (Alectinib) make sure your physician is aware of any allergies or medications you currently take, and current medical conditions.  Alectinib can cause bradycardia, hepatotoxicity, myalgia, pulmonary toxicity in the form of severe interstitial lung disease (ILD), and renal toxicity all of which may require therapy interruption and/or dose reduction.  Alectinib should only be considered for patients who have been tested for the presence of abnormal ALK positivity in tumor tissue or plasma specimens. 

Avoid sun exposure during treatment and for up to 7 days after the final Alectinib dose).  Make sure to use a broad spectrum sunscreen and lip balm (SPF ≥50).

What if I miss a dose?

If a dose is missed or if vomiting occurs, administer the next dose at the regularly scheduled time. Do not take double or extra doses to make up for the missed dose.

How should I store this medication?

Keep out of the reach of children at all times. Store at room temperature, 59 to 86° F (15 to 30° C). Protect from light. Keep the container tightly closed. Properly dispose of any unused medication after the expiration date.

What are the possible side effects of using this medication? 

Edema, bradycardia, fatigue, headache , skin rash, hyperglycemia, hypocalcemia,  hypokalemia, hypophosphatemia, hyponatremia, weight gain, constipation, nausea, diarrhea, vomiting, anemia, lymphocytopenia, increased serum AST and  alkaline phosphatase, hyperbilirubinemia, musculoskeletal pain, myalgia, back pain, cough, dyspnea, pulmonary embolism, skin photosensitivity, visual disturbances. 

Note this is not a complete list of side effects for ALECENSA/ALECENSARO (Alectinib), only common ones.