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What is this medication? 

AXERT (Almotriptan)
Antimigraine; Serotonin 5-HT1B/1D Receptor Agonist

Almotriptan is officially indicated to treat acute migraines with or without aura. 

How does this medication work? 

AXERT (Almotriptan) is a selective agonist for serotonin 5-HT1B and 5-HT1D receptors.  These are located on intracranial blood vessels and sensory nerves of the trigeminal system and activating these receptors causes vasoconstriction and reduces neurogenic inflammation associated with antidromic neuronal transmission.

How should I take this medication? 

Oral: Take 6.25-12.5mg per dose, can repeat dose after 2 hours if only partial relief or if symptoms return to a maximum of 25mg/24 hours.  Safety of treating over 4 headaches per month has not been established.

How to Take: Follow instructions provided by physician/pharmacy label, with or without food, use at first sign of migraine symptoms.

What should I watch for while using this medication? 

Before starting AXERT (Almotriptan), make sure your physician is aware of any allergies (Sulfa) or medications you currently take (MAO inhibitors/ergotamine derivatives), if you have any cardiovascular disease, cerebrovascular disease, liver disease, kidney disease, a history of hemiplegic migraine, ophthalmoplegic migraine, are pregnant, or breastfeeding.  This medication has risk of causing serotonin syndrome especially if combined with other serotonergic drugs.  Before triptans are used a full cardiac workup including ECG may be considered.

Do not use triptans more than 10 times per month to avoid medication overuse headache.  

What if I miss a dose?

If you miss a dose of medication, try to take it as soon as possible. However, if it is almost time for your next dose, take only that scheduled dose. Do not take double or extra doses.

How should I store this medication?

Keep out of the reach of children at all times. Store at room temperature, 59 to 86° F (15 to 30° C). Protect from light. Keep the container tightly closed. Properly dispose of any unused medication after the expiration date.

What are the possible side effects of using this medication?

Nausea, headache, dizziness, drowsiness, tingling sensation.

Note this is not a complete list of side effects for AXERT (Almotriptan), only common ones.