ATACAND PLUS (Candesartan/ Hydrochlorothiazide)
ATACAND PLUS (Candesartan/ Hydrochlorothiazide)
ATACAND PLUS (Candesartan/ Hydrochlorothiazide)
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ATACAND PLUS (Candesartan/ Hydrochlorothiazide)

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What is this medication?

ATACAND PLUS (Candesartan/Hydrochlorothiazide)
Antihypertensive Agent, Angiotensin II Receptor Blocker

ATACAND PLUS is a combination of 2 drugs, Candesartan and Hydrochlorothiazide, which are indicated for the management of hypertension; high blood pressure.

When pregnancy is detected, discontinue candesartan as soon as possible. Drugs that act directly on the renin-angiotensin system can cause injury and even death to the developing fetus.

How does this medication work? 

Angiotensin II constricts blood vessels and stimulates the release of aldosterone. Aldosterone increases sodium and water reabsorption which increases blood volume thereby elevating blood pressure. Candesartan inhibits angiotensin II resulting in the opposite effect.

Hydrochlorothiazide lowers blood pressure by inhibiting sodium reabsorption in the distal tubules which causes increased loss of sodium, water, potassium, and hydrogen ions (lower blood volume results in decreased pressure).  It is also believed to lower peripheral vascular resistance (by relaxing blood vessels).

How should I take this medication? 

Oral: Once you are stabilized on the individual components, take 1 (16 mg/12.5 mg, 32 mg/12.5 mg or 32 mg/25 mg) tablet once daily.

How to Take: Follow instructions provided by physician/pharmacy label. Take with or without food.

What should I watch for while using this medication? 

Before starting ATACAND PLUS (Candesartan/Hydrochlorothiazide), make sure your physician is aware of any allergies or medications you currently take, if you have kidney disease, an electrolyte imbalance, liver disease, are pregnant or breastfeeding.

What if I miss a dose?

If you miss a dose of medication, try to take it as soon as possible. However, if it is almost time for your next dose, take only that scheduled dose. Do not take double or extra doses.

How should I store this medication?

Keep out of the reach of children at all times. Store at room temperature, 59 to 86° F (15 to 30° C). Protect from light. Keep the container tightly closed. Properly dispose of any unused medication after the expiration date.

What are the possible side effects of using this medication?

Hypotension, renal function abnormality, dizziness, hyperkalemia, worsening of hyperuricemia (can result in gout attacks).

Note this is not a complete list of side effects for ATACAND PLUS (Candesartan/Hydrochlorothiazide), only common ones.