CYKLOKAPRON (Tranexamic Acid)
CYKLOKAPRON (Tranexamic Acid)
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CYKLOKAPRON (Tranexamic Acid)

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What is this medication?

CYKLOKAPRON (Tranexamic Acid)
Antifibrinolytic AgentAntihemophilic AgentHemostatic AgentLysine Analog

CYKLOKAPRON (Tranexamic Acid) is indicated for the treatment in menstrual bleeding, heavy (oral); tooth extraction in patients with hemostatic defects (injection, oral).

How does this medication work?

CYKLOKAPRON (Tranexamic Acid) forms a reversible complex that displaces plasminogen from fibrin resulting in inhibition of fibrinolysis.  It also inhibits plasmin proteolytic activity.

How should I take this medication?

Menstrual Bleeding
Oral: Take 1 to 1.5 g three to four times daily for several days during menstruation.

Tooth extraction in patients with hemostatic defects
Oral: Take 25 mg/kg (usual dose range: 1 to 1.5 g) given 2 hours prior to procedure, then 25 mg/kg (usual dose range: 1 to 1.5 g) 3 to 4 times daily for up to 7 to 10 days.

IV: Inject 10 mg/kg intravenously using actual body weight (usual dose range: 500 mg to 1 g) administered ~2 hours before procedure at a rate not to exceed 100 mg/minute (generally over 10 to 20 minutes), then 10 mg/kg IV 3 to 4 times daily.

How to Take: May be administered by direct IV injection at a maximum rate of 100 mg/minute as faster rates may cause hypotension.  Oral formulations can be administered without regard to meals. Swallow tablet whole; do not break, chew, or crush. Consider for use in women who decline or should not use hormonal therapy. Start once heavy menstrual bleeding has begun.

What should I watch for while using this medication?

Before starting CYKLOKAPRON (Tranexamic Acid), make sure your physician is aware of any allergies or medications you currently take, if you have disseminated intravascular coagulation, renal impairment, subarachnoid hemorrhage, vascular disease, are pregnant, or breastfeeding. Tranexamic Acid use has been associated with rare but serious adverse events such as dizziness, hypersensitivity reactions, ocular effects, seizure, and thrombotic events.

What if I miss a dose?

If you miss a dose of medication, try to take it as soon as possible.  However, if it is almost time for your next dose, take only that scheduled dose.  Do not take double or extra doses.

How should I store this medication?

Keep out of the reach of children at all times.  Store at room temperature, 59 to 86° F (15 to 30° C).  Protect from light.  Keep the container tightly closed.  Properly dispose of any unused medication after the expiration date.

What are the possible side effects of using this medication?

Abdominal pain, headache, back pain, musculoskeletal pain, nasal signs/symptoms.

Note this is not a complete list of side effects for CYKLOKAPRON (Tranexamic Acid), only common ones.