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What is this medication?


Dapsone is indicated for the treatment of leprosy, and dermatitis herpetiformis.

How does this medication work? 

Dapsone exhibits anti-bacterial and anti-protozoa activity that inhibits the synthesis of dihydrofolic acid through by competing with para-aminobenzoic acid for the active site of dihydropteroate synthetase.

How should I take this medication? 

Oral: Take 50mg to 300mg daily.

How to Take: Take tablets with meals if gastric irritation occurs.

What should I watch for while using this medication? 

Before starting Dapsone, make sure your physician is aware of any allergies or medications you currently take, and activities you perform.  Dapsone has been reported to cause aplastic anemia, agranulocytosis, and dyscrasias (some fatal); the patient should be closely monitored for signs/symptoms of fever, sore throat, pallor, purpura and jaundice.  Dapsone can cause serious dermatologic reactions, hepatic effects, peripheral neuropathy, and fungal or bacterial superinfections.  Dapsone should be used with caution in patients with anemia and diabetes mellitus.

What if I miss a dose?

If you miss a dose of medication, try to take it as soon as possible. However, if it is almost time for your next dose, take only that scheduled dose. Do not take double or extra doses.

How should I store this medication?

Keep out of the reach of children at all times. Store at room temperature, 59 to 86° F (15 to 30° C). Protect from light. Keep the container tightly closed. Properly dispose of any unused medication after the expiration date.

What are the possible side effects of using this medication?
Reticulocyte increase, hemolysis, hemoglobin decrease, methemoglobinemia, red cell life span shortened, fever, headache, insomnia, psychosis, vertigo, abdominal pain, nausea, pancreatitis, vomiting, blurred vision, infectious mononucleosis-like syndrome (rash, fever, lymphadenopathy, hepatic dysfunction).

Note this is not a complete list of side effects for Dapsone, only common ones.