DIPENTUM (Olsalazine)

DIPENTUM (Olsalazine)

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What is this medication?

DIPENTUM (Olsalazine)
5-Aminosalicylic Acid Derivative

DIPENTUM (Olsalazine) is officially indicated for remission maintenance of ulcerative colitis in patients intolerant to sulfasalazine.

How does this medication work? 

Mesalamine is the active component of Olsalazine. It is a 5-aminosalicylic acid derivative that is essentially a controlled release form of mesalamine and has been found to exhibit anti-inflammatory properties.  The exact mechanism of action is unknown; but it is thought to modulate local inflammatory mediators such as leukotrienes and tumor necrosis factor.  

How should I take this medication? 

Oral: Take 1g daily in divided doses.

How to Take: Swallow the capsule whole and do not crush or chew it.  Take with a meal in evenly divided doses.

What should I watch for while using this medication? 

Use DIPENTUM (Olsalazine) with caution in patients with pericarditis and myocarditis. Discontinue use in patients who experience hypersensitivity reactions which may include hepatitis, myocarditis, pericarditis, nephritis, hematologic abnormalities and/or pneumonitis. Olsalazine may exacerbate symptoms of colitis. Use with cautions in patients with asthma, hepatic and renal impairment.

What if I miss a dose?

If you miss a dose of medication, try to take it as soon as possible. However, if it is almost time for your next dose, take only that scheduled dose. Do not take double or extra doses.

How should I store this medication?

Keep out of the reach of children at all times. Store at room temperature, 59 to 86° F (15 to 30° C). Protect from light. Keep the container tightly closed. Properly dispose of any unused medication after the expiration date.

What are the possible side effects of using this medication?


Note this is not a complete list of side effects for DIPENTUM (Olsalazine), only common ones.