ENTOCORT (Budesonide)

ENTOCORT (Budesonide)

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What is this medication?

ENTOCORT (Budesonide)

ENTOCORT (Budesonide) is officially indicated for the treatment of mild to moderate Crohn disease.

How does this medication work? 

ENTOCORT (Budesonide) is a synthetic glucocorticoid that acts within the gastrointestinal tract and only has a weak systemic effect.  The exact mechanism of action of Budesonide is not known but is believed to be due to its ability to supress inflammatory mediators and the body’s immunological response to inflammation.

Budesonide is formulated to as a controlled release capsule that contains enteric coated granules that dissolve at a pH ≥5.5, delivering budesonide to the ileum and ascending colon. 

How should I take this medication? 

Oral: Take 9mg once daily in the morning for up to 8 weeks; recurring episodes may be treated with a repeat 8-week course of treatment.

*Following treatment of the active disease, treatment can be continued at a daily dose of 6mg for up to 3 months.  If symptom control is maintained for 3 months, tapering of the dosage to complete cessation is recommended.

How to Take: It is best to take ENTOCORT (Budesonide) in the morning with or without meals.  Swallow the capsule whole and do not crush or chew it.  Budesonide capsules can be opened and the granules sprinkled on applesauce and consume within 30 minutes.  Do not chew or crush the granules.

What should I watch for while using this medication?

Before starting ENTOCORT (Budesonide), make sure your physician is aware of any allergies or medications you currently take. Budesonide can cause hypercortisolism or suppression of the hypothalamic-pituitary-adrenal (HPA) axis, particularly in young children or if receiving high doses for prolonged periods. Budesonide can cause an increase in risk of secondary infections due to immunosuppression associated with prolonged use of corticosteroids. Budesonide can cause development of Kaposi sarcoma, myopathy, and psychiatric disturbances. Use Budesonide with caution in patients with heart failure, hypertension, diabetes, gastrointestinal disease, ocular disease, myasthenia gravis, osteoporosis, seizures disorders, hepatic and renal impairment.

What if I miss a dose?

If you miss a dose of medication, try to take it as soon as possible. However, if it is almost time for your next dose, take only that scheduled dose. Do not take double or extra doses.

How should I store this medication?

Keep out of the reach of children at all times. Store at room temperature, 59 to 86° F (15 to 30° C). Protect from light. Keep the container tightly closed.  Properly dispose of any unused medication after the expiration date.

What are the possible side effects of using this medication? 

Headache, acne vulgaris, decreased cortisol, bruise (15%), nausea, respiratory tract infection.

Note this is not a complete list of side effects for ENTOCORT (Budesonide), only common ones.