EXTINA/KETODERM (Ketoconazole)

EXTINA/KETODERM (Ketoconazole)

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TARO PHARMACEUTICALS
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$39.99 USD
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prescription

What is this medication?

EXTINA/KETODERM (Ketoconazole)
Antifungal Agent (Topical)

Brand Name US: Extina, Ketodan
Canadian Equivalent: Ketoderm

EXTINA/KETODERM (Ketoconazole) is indicated for treatment of cutaneous candidiasis, seborrheic dermatitis, tinea corporis, cruris, pedis.

ALERT: WARNING
Only use ketoconazole when other antifungal therapy is not readily available or tolerated and the potential benefits outweigh the risks.  Serious hepatotoxicity causing fatality or requiring liver transplantation have occurred with the use of oral ketoconazole.  Avoid using ketoconazole with dofetilide, quinidine, pimozide, cisapride, methadone, disopyramide, dronedarone and ranolazine because of the risk of QT prolongation.

How does this medication work? 

EXTINA/KETODERM (Ketoconazole) is an azole antifungal that inhibits the biosynthesis of triglycerides and phospholipids and cytochrome P450 enzyme required for the conversion of lanosterol to ergosterol.  This results in increased fungal cell permeability due to reduced amounts of ergosterol present in the fungal cell membrane.

How should I take this medication? 

Topical: Apply to the affected areas once to twice daily for 2 to 4 weeks; or until clinical response. 

How to Take: To be applied externally; not for ophthalmic, oral or intravaginal use. Avoid contact with the eyes and other mucous membranes.  Wash hands after application.

What should I watch for while using this medication? 

Before starting EXTINA/KETODERM (Ketoconazole), make sure your physician is aware of any allergies or medications you currently take, existing medical conditions, activities you perform.  Ketoconazole can suppress adrenocortical function, increase bone fragility leading to fracture, increase the risk of myopathy.  Avoid taking ketoconazole concomitantly with drugs (proton pump inhibitors, antacids, H2-blockers) that reduce acidity, and to treat fungal meningitis.

What if I miss a dose?

If you miss a dose of this medicine, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.

How should I store this medication?

Keep out of the reach of children at all times. Store at room temperature, and do not freeze. Protect from light, heat, and moisture. Keep the container tightly closed. Properly dispose of any unused medication after the expiration date.

What are the possible side effects of using this medication?

Itching, stinging, burning, or irritation not present before use of this medicine, acne, blistering, crusting, irritation, itching, or reddening of the skin, burning, crawling, itching, numbness, prickling, “pins and needles”, or tingling feelings, cracked, dry, or scaly skin.

Note this is not a complete list of side effects for EXTINA/KETODERM (Ketoconazole), only common ones.