SILVADENE/FLAMAZINE (Silver Sulfadiazine)

SILVADENE/FLAMAZINE (Silver Sulfadiazine)

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What is this medication?

SILVADENE/FLAMAZINE (Silver Sulfadiazine)
Topical Antibiotic

SILVADENE/FLAMAZINE (Silver Sulfadiazine) is indicated for burn treatment.

How does this medication work? 

Acts upon the bacterial cell wall and cell membrane. Bactericidal for many gram-negative and gram-positive bacteria and is effective against yeast.

How should I take this medication? 

Topical: Apply to a thickness of 1/16 inch once or twice daily; reapply as needed to areas where the cream is removed by patient activity as the burned area should be covered with cream at all times. Continue use until healing has occurred or the burn site is ready for grafting. Do not discontinue therapy if the possibility of infection exists unless a significant adverse reaction has occurred.

How to Take: For topical use only; avoid contact with eyes. Apply with a sterile-gloved hand. Burned area should be covered with cream at all times; reapply to areas where cream has been removed by patient activity. Dressings may be used if necessary. Reapply immediately after hydrotherapy.

What should I watch for while using this medication? 

Before starting use of SILVADENE/FLAMAZINE (Silver Sulfadiazine), make sure your physician is aware of any allergies (Sulfa) or medications you currently take, if you have G6PD deficiency, hepatic impairment, real impairment, if you are pregnant, or breastfeeding. Silver Sulfadiazine (Topical) use has been associated with hypersensitivity reactions, systemic side effects and antibiotic resistant superinfection from prolonged use.

What if I miss a dose?

If you miss a dose of medication, try to take it as soon as possible. However, if it is almost time for your next dose, take only that scheduled dose. Do not take double or extra doses.

How should I store this medication?

Keep out of the reach of children at all times. Store at room temperature, 59 to 86° F (15 to 30° C). Protect from light. Keep the container tightly closed. Properly dispose of any unused medication after the expiration date.

What are the possible side effects of using this medication?

Erythema multiforme, pruritus, skin discoloration, skin photosensitivity, skin rash, agranulocytosis, aplastic anemia, hemolytic anemia, leukopenia, hepatitis, hypersensitivity reaction (may be related to sulfa component), interstitial nephritis.

Note this is not a complete list of side effects for SILVADENE/FLAMAZINE (Silver Sulfadiazine), only common ones.