FOSAMAX PLUS D/FOSAVANCE (Alendronate/Cholecalciferol)
FOSAMAX PLUS D/FOSAVANCE (Alendronate/Cholecalciferol)
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FOSAMAX PLUS D/FOSAVANCE (Alendronate/Cholecalciferol)

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What is this medication? 

FOSAMAX PLUS D/FOSAVANCE (Alendronate/Cholecalciferol)
Bisphosphonate, Vitamin D Analog

Brand Name US: Fosamax Plus D
Canadian Equivalent: Fosavance

Alendronate/Cholecalciferol is indicated for the treatment of osteoporosis.

Limitations of use: Not for use in the treatment of vitamin D deficiency.

How does this medication work? 

Alendronate is a bisphosphonate that inhibits osteoclasts and slows down bone resorption allowing osteoblasts to work more effectively to build bone mass.

Cholecalciferol is a fat-soluble vitamin that helps the body absorb calcium and phosphorus increasing bone mineralization.

How should I take this medication? 

Oral: Take 1 tablet (alendronate 70mg/cholecalciferol 2800 units or 5600 units) once weekly.

How to Take:  Take in the morning at least 30 minutes before breakfast, with a full glass of water.  Swallow whole; do not chew or crush the tablet.  Do not lie down for ≥30 minutes and until after first food of the day (to reduce esophageal irritation).

Note: Patients should receive supplemental calcium if dietary intake is inadequate. Some patients may require additional vitamin D while taking this product (not intended to treat vitamin D deficiency).

What should I watch for while using this medication?  

Before starting FOSAMAX PLUS D/FOSAVANCE (Alendronate/Cholecalciferol), make sure your physician is aware of any allergies or medications you currently take, and current medical conditions.  Atypical femur fractures, severe joint and bone pain, gastrointestinal irritation, ocular effects and osteonecrosis of the jaw can occur when taking Alendronate/Cholecalciferol.  Use with caution in patients with hypercalcemia and/or hypercalciuria, undergoing bariatric surgery, and renal impairment.

What if I miss a dose?

If a once-weekly dose is missed, administer the next morning after remembered. Then return to the original scheduled day of the week on the once-weekly schedule; however, do not administer 2 doses on the same day.

How should I store this medication?

Keep out of the reach of children at all times. Store at room temperature, 59 to 86° F (15 to 30° C). Protect from light. Keep the container tightly closed. Properly dispose of any unused medication after the expiration date.

What are the possible side effects of using this medication?

Headache, abdominal pain, dyspepsia, constipation, diarrhoea, flatulence, ulcers in the oesophagus, dysphagia, abdominal distension, acid regurgitation and musculoskeletal pain.

Note this is not a complete list of side effects for FOSAMAX PLUS D/FOSAVANCE (Alendronate/Cholecalciferol), only common ones.