LAMISIL (Terbinafine)
LAMISIL (Terbinafine)
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LAMISIL (Terbinafine)

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What is this medication?

LAMISIL (Terbinafine)
Antifungal Agent

LAMISIL (Terbinafine) is officially indicated to treat onychomycosis, tinea capitis and other dermatologic fungal infections depending on the formulation.

How does this medication work?

Terbinafine/Lamisil is a synthetic allylamine derivative that inhibits squalene epoxidase, a key enzyme in sterol biosynthesis in fungi. This results in a deficiency in ergosterol within the fungal cell membrane and results in fungal cell death.

How should I take this medication?

Oral: Take 250mg once daily for 6 weeks (fingernail) and/or 12 weeks (toenail).

Tinea Pedis, Tinea Corporis, Tinea Cruris
Topical (Cream, Spray):  Apply to the affected area once daily for 1 week.

Cutaneous Candidiasis
Topical (Cream):  Apply to the affected areas once to twice daily for 1 to 2 weeks.

Tinea Versicolor
Topical (Cream, Spray):  Apply to the affected areas once to twice daily for 1 to 2 weeks.

How to Take: When administering Terbinafine orally, you can take the tablets with/without food; for the granules take with non-acidic food and swallow the granules whole without chewing them.  When applying Terbinafine topically, wash your hands before and after application. 

What should I watch for while using this medication?

Use LAMISIL (Terbinafine) in caution in patients with allylamine antifungal sensitivity.

Can cause taste disturbance .

Hepatic failure has been reported in patients with and without pre-existing hepatic disease.  Do not use in patients with hepatic impairment.

Serious skin and hypersensitivity reactions including (i.e. Stevens-Johnson syndrome, toxic epidermal necrolysis, erythema multiforme, exfoliative dermatitis, bullous dermatitis, drug reaction with eosinophilia and systemic symptoms [DRESS] syndrome) have occurred. 

Smell disturbance (including loss of smell) has been reported.

Thrombotic microangiopathy (TMA), including thrombotic thrombocytopenic purpura and hemolytic uremic syndrome, have been reported (some fatal).

Use with caution in patients with renal impairment.

What if I miss a dose?

If you miss a dose of medication, try to take it as soon as possible.  However, if it is almost time for your next dose, take only that scheduled dose.  Do not take double or extra doses.

How should I store this medication?

Keep out of the reach of children at all times.  Store at room temperature, 59 to 86° F (15 to 30° C).  Protect from light.  Keep the container tightly closed.  Properly dispose of any unused medication after the expiration date.

What are the possible side effects of using this medication?

Headache, local irritation. If irritation/sensitivity develops, discontinue therapy and institute appropriate.

Note this is not a complete list of side effects for LAMISIL (Terbinafine), only common ones.