LEXIVA/TELZIR (Fosamprenavir)

LEXIVA/TELZIR (Fosamprenavir)

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VIIV HEALTHCARE
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$714.99 USD
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prescription

What is this medication?

LEXIVA/TELZIR (Fosamprenavir)
Pro-drug, HIV-1 protease inhibitor

Brand Name US: Lexiva
Canadian Equivalent: Telzir

LEXIVA/TELZIR (Fosamprenavir) is indicated in combination with other antiretroviral agents for the treatment of human immunodeficiency virus (HIV-1) infection.

How does this medication work? 

LEXIVA/TELZIR (Fosamprenavir) is a pro-drug of the protease inhibitor and antiretroviral drug amprenavir.  Fosamprenavir is a pro-drug that is rapidly hydrolyzed to amprenavir by cellular phosphatases in the gut epithelium as it is absorbed. Amprenavir binds to the active site of HIV-1 protease and thereby prevents the processing of viral Gag and Gag-Pol polyprotein precursors, resulting in the formation of immature non-infectious viral particles. LEXIVA is used in combination with other antiretroviral agents for the treatment of 4 human immunodeficiency virus (HIV-1) infections.

How should I take this medication? 

Oral: Take 1400mg twice daily.
Oral: Take 1400mg once daily plus ritonavir 200mg once daily.
Oral: Take 1400mg plus ritonavir 100mg once daily. 
Oral: Take 700mg twice daily plus ritonavir 100mg twice daily.

How to Take: Administer with or without food.

What should I watch for while using this medication? 

Before starting LEXIVA/TELZIR (Fosamprenavir), make sure your physician is aware of any allergies or medications you currently take.  Fosamprenavir has been associated with several serious side effects including Stevens-Johnson syndrome.  Fosamprenavir should be used with caution in patients with a known sulfonamide allergy. Patients with hepatitis B or C are at increased risk of transaminase elevations. Patients receiving Fosamprenavir may develop new onset or exacerbations of diabetes mellitus, hyperglycemia, immune reconstitution syndrome, redistribution/accumulation of body fat and elevated triglyceride and cholesterol concentrations. Monitor cholesterol and triglycerides prior to therapy and periodically thereafter.

What if I miss a dose?

If you miss a dose of medication, try to take it as soon as possible. However, if it is almost time for your next dose, take only that scheduled dose. Do not take double or extra doses.

How should I store this medication?

Keep out of the reach of children at all times. Store at room temperature, 59 to 86° F (15 to 30° C). Protect from light. Keep the container tightly closed. Properly dispose of any unused medication after the expiration date.

What are the possible side effects of using this medication?

Diarrhea, rash, nausea, vomiting, headache.

Note this is not a complete list of side effects for LEXIVA/TELZIR (Fosamprenavir), only common ones.