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What is this medication?

Diuretic, Carbonic Anhydrase InhibitorOphthalmic Agent, Antiglaucoma

Methazolamide is indicated for treatment of glaucoma.

How does this medication work? 

Methazolamide is a noncompetitive carbonic anhydrase inhibitor.  Carbonic anhydrase is found in the cells of the luminal border of the proximal tubule of the nephron.  When inhibited it increases urine volume and pH with a subsequent decrease in the excretion of titratable acid and ammonia.

How should I take this medication?

Oral: Take 50 to 100 mg 2 to 3 times/day.

How to Take: Follow instructions provided by physician/pharmacy label, take consistently at same times each day unless otherwise directed.

What should I watch for while using this medication? 

Before starting Methazolamide make sure your physician is aware of any allergies (sulfa) or medications you currently take, if you have kidney dysfunction, liver dysfunction, adrenal gland failure, hyperchloremic acidosis, hyponatremia, hypokalemia, angle closure glaucoma, diabetes, are pregnant, or breastfeeding. Methazolamide use has been associated with rare but serious adverse events such as impaired mental alertness, impaired physical coordination, and electrolyte disturbances.

What if I miss a dose?

If you miss a dose of medication, try to take it as soon as possible.  However, if it is almost time for your next dose, take only that scheduled dose.  Do not take double or extra doses.

How should I store this medication?

Keep out of the reach of children at all times.  Store at room temperature, 59 to 86° F (15 to 30° C).  Protect from light.  Keep the container tightly closed.  Properly dispose of any unused medication after the expiration date.

What are the possible side effects of using this medication?

Confusion, drowsiness, fatigue, flaccid paralysis, malaise, paresthesia, seizure, erythema multiforme, skin photosensitivity, skin rash, Stevens-Johnson syndrome, toxic epidermal necrolysis, urticaria, electrolyte disturbance, glycosuria, metabolic acidosis, decreased appetite, diarrhea, dysgeusia, melena, nausea, vomiting, crystalluria, hematuria, agranulocytosis, aplastic anemia, bone marrow depression, hemolytic anemia, immune thrombocytopenia, leukopenia, pancytopenia, fulminant hepatic necrosis, hepatic insufficiency, anaphylaxis, hypersensitivity reaction, myopia, auditory disturbance, tinnitus, nephrolithiasis, polyuria, fever.

Note the frequency of side effects have not been determined.