ORILISSA (Elagolix)
ORILISSA (Elagolix)
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ORILISSA (Elagolix)

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What is this medication?

ORILISSA (Elagolix)
Gonadotropin Releasing Hormone Antagonist

ORILISSA (Elagolix) is indicated for treatment of endometriosis.

How does this medication work?

ORILISSA (Elagolix) is a gonadotropin-releasing hormone antagonist that suppresses pituitary and ovarian hormone function in a dose-dependent manner.

How should I take this medication?

Oral: 150mg once daily.

How to Take: Take at the same time each day with or without food. Treatment should be initiated within 7 days of menses onset otherwise pregnancy must be excluded prior to therapy.

What should I watch for while using this medication?

Before starting ORILISSA (Elagolix) make sure your physician is aware of any allergies or medications you currently take.  ORILISSA (Elagolix) can cause irregularities in menstrual bleeding patterns. A loss in bone mineral density and hepatic impairment has been associated with using ORILISSA (Elagolix)

What if I miss a dose?

If you miss a dose of medication, try to take it as soon as possible.  However, if it is almost time for your next dose, take only that scheduled dose.  Do not take double or extra doses.

How should I store this medication?

Keep out of the reach of children at all times.  Store at room temperature, 59 to 86° F (15 to 30° C).  Protect from light.  Keep the container tightly closed.  Properly dispose of any unused medication after the expiration date.

What are the possible side effects of using this medication?

Headache, night sweats, amenorrhea, hot flash, nausea, loss in bone mineral density, insomnia, depressed mood, depression, anxiety, decrease libido, weight gain, abdominal pain, constipation, diarrhea, elevated liver enzymes, joint pain.

Note this is not a complete list of side effects for ORILISSA (Elagolix), only common ones.