PIQRAY (Alpelisib)
PIQRAY (Alpelisib)
PIQRAY (Alpelisib)
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PIQRAY (Alpelisib)

Vendor
NOVARTIS PHARMACEUTICALS
Regular price
$7,699.99 USD
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$7,699.99 USD
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prescription

What is this medication? 

PIQRAY (Alpelisib)
Antineoplastic Agent, Phosphatidylinositol 3-Kinase Inhibitor

PIQRAY (Alpelisib) is a kinase inhibitor indicated in combination with fulvestrant for the treatment of postmenopausal women, and men, with hormone receptor (HR)- positive, human epidermal growth factor receptor 2 (HER2)-negative, PIK3CA-mutated, advanced or metastatic breast cancer as detected by an FDA-approved test following progression on or after an endocrine-based regimen.

How does this medication work? 

PIQRAY (Alpelisib) blocks the PI3Kα and Akt-signalling pathway, while overcoming endocrine treatment resistance in HR-positive advanced breast cancer patients. PI3K inhibition has shown to induce ER transcription increase in breast cancer cells.

How should I take this medication? 

Oral: Take 300mg daily.

How to Take: Take with food at the same time each day. Swallow the tablets whole; do not crush, split or chew.

What should I watch for while using this medication? 

Before starting PIQRAY (Alpelisib) make sure your physician is aware of any allergies or medications you currently take. Alpelisib have been shown to cause dermatologic toxicity (i.e. Stevens-Johnson syndrome (SJS) and erythema multiforme), gastrointestinal toxicity, hyperglycemia and pulmonary toxicity (i.e. interstitial lung disease).

What if I miss a dose?

If a dose is missed, it can be taken with food within 9 hours after the time it is usually taken. After more than 9 hours, skip the dose for that day. The next day, take at the usual time. Do not take 2 doses to make up for a missed dose.

How should I store this medication?

Keep out of the reach of children at all times. Store at room temperature, 59 to 86° F (15 to 30° C).  Protect from light. Keep the container tightly closed. Properly dispose of any unused medication after the expiration date.

What are the possible side effects of using this medication? 

Peripheral edema, fatigue, headache, skin rash, alopecia, pruritus, xeroderma, hyperglycemia, diarrhea, decrease appetite, weight loss, nausea, abdominal pain, dry mucous membranes, dyspepsia, nasopharyngitis, upper respiratory tract infection, lymphocytopenia, fever.

Note this is not a complete list of side effects for PIQRAY (Alpelisib), only common ones.