PROCYTOX (Cyclophosphamide)

PROCYTOX (Cyclophosphamide)

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What is this medication?

PROCYTOX (Cyclophosphamide)
Antineoplastic Agent, 
Alkylating Agent; Antirheumatic, Immunosuppressant Agent

Acute Lymphoblastic leukemia, acute myeloid leukemia, breast cancer, chronic lymphocytic leukemia, chronic myeloid leukemia (CML), Hodgkin lymphoma, mycosis fungoides, multiple myeloma, neuroblastoma, non-Hodgkin lymphomas (including Burkitt lymphoma), ovarian adenocarcinoma, and retinoblastoma. Nephrotic syndrome

How does this medication work?

PROCYTOX (Cyclophosphamide) is an alkylating agent that prevents cell division by cross-linking DNA strands and decreasing DNA synthesis. It is a cell cycle phase nonspecific agent. PROCYTOX (Cyclophosphamide) also possesses potent immunosuppressive activity.

How should I take this medication?

Oral: 1mg/kg to 5mg/kg once daily or 50mg to 150mg once daily.

How to Use:
Oral: Preferably taken in the morning to ensure adequate hydration throughout the day.  Swallow the capsule whole; do not crush, chew or open the capsule.  Avoid exposure to broken capsules; if contact occurs, wash hands immediately and thoroughly.

What should I watch for while using this medication?

Before starting PROCYTOX (Cyclophosphamide) make sure your physician is aware of any allergies or medications you currently take. PROCYTOX (Cyclophosphamide) can cause serious adverse effects such as bone marrow suppression (i.e. leukopenia, neutropenia, thrombocytopenia, anemia), cardiotoxicity, hepatotoxicity, immunosuppression which will require monitoring for infections, pulmonary toxicities (i.e. pneumonitis, pulmonary fibrosis, pulmonary veno-occlusive disease, acute respiratory distress syndrome), secondary malignancies (i.e. bladder cancer, myelodysplasia, acute leukemias, lymphomas, thyroid cancer, sarcomas), urinary and renal toxicity.

What if I miss a dose?

If you miss a dose of medication, try to take it as soon as possible.  However, if it is almost time for your next dose, take only that scheduled dose.  Do not take double or extra doses.

How should I store this medication?

Keep out of the reach of children at all times.  Store at room temperature, 59 to 86° F (15 to 30° C).  Protect from light.  Keep the container tightly closed.  Properly dispose of any unused medication after the expiration date.

What are the possible side effects of using this medication?

Alopecia, changes in hormonal levels, amenorrhea, abdominal pain, diarrhea, mucositis, nausea, vomiting, stomatitis, azoospermia, defective oogenesis, hemorrhagic cystitis, oligospermia, sterility, infection.

Note this is not a complete list of side effects for PROCYTOX (Cyclophosphamide), only common ones.