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What is this medication? 

Nonsteroidal Anti-Inflammatory Drugs

Sulindac in indicated for treatment of gouty arthritis, ankylosing spondylitis, bursitis/tendinopathy, osteoarthritis, rheumatoid arthritis.

“Alert US Warning:

FDA has issued a warning on the use of NSAIDs from 20 weeks gestation or later in pregnancy can lead to fetal renal dysfunction leading to oligohydramnios, neonatal renal impairment which may be fatal.  NSAIDs cause an increased risk of cardiovascular thrombotic events, including myocardial infarction and stroke, which can be fatal. Sulindac is contraindicated in coronary artery bypass graft (CABG) surgery.  NSAIDs cause an increased risk of serious gastrointestinal adverse events such as bleeding, ulceration and perforation of the stomach or intestines, which can be fatal.”

How should I take this medication? 

Usual (Oral): 150mg to 200mg twice daily for 7 to 14 days.

How to Take Sulindac:  Take with food

What should I watch for while using this medication? 

Before starting sulindac make sure your physician is aware of any allergies or medications you currently take, and activities you perform.  Sulindac like other NSAIDs cause an increased risk of serious and potentially fatal cardiovascular thrombotic events, including myocardial infarction and stroke.   Sulindac can cause drug reactions characterized with eosinophilia and systemic symptoms.  Sulindac does increase the risk of serious gastrointestinal conditions such an ulceration, bleeding and perforation.  Sulindac has also been associated with persistent urinary symptoms (bladder pain, dysuria, urinary frequency), decreased platelet adhesion and aggregation, hyperkalemia, pancreatitis, and potentially serious skin reactions including exfoliative dermatitis, Stevens-Johnson syndrome (SJS), and toxic epidermal necrolysis (TEN); may occur without warning.  Sulindac should be used with caution in patients with aseptic meningitis, asthma, coronary artery bypass graft (CABG) surgery, hepatic and/or renal impairment.

What if I miss a dose?

If you miss a dose of medication, try to take it as soon as possible. However, if it is almost time for your next dose, take only that scheduled dose. Do not take double or extra doses.

How should I store this medication?

Keep out of the reach of children at all times. Store at room temperature, 59 to 86° F (15 to 30° C). Protect from light. Keep the container tightly closed. Properly dispose of any unused medication after the expiration date.

What are the possible side effects of using this medication?

Edema, pruritus, skin rash, dizziness, headache, nervousness, abdominal cramps, anorexia, constipation, diarrhea, dyspepsia, flatulence, gastrointestinal pain, nausea, vomiting, tinnitus

Note: this is not a complete list of side effects, only the most common.