Teveten Plus (Eprosartan/ Hydrochlorothiazide)

Teveten Plus (Eprosartan/ Hydrochlorothiazide)

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What is this medication?

Eprosartan+Hydrochlorothiazide, Teveten Plus
Angiotensin II Receptor Blocker, Diuretic

Eprosartan+Hydrochlorothiazide, Teveten Plus is indicated for treatment of hypertension.

“Special Alert: Health Canada

Diuretics Safety Alert
Diuretics such as hydrochlorothiazide have been linked to developing choroidal effusion (CE), acute myopia (AM), and narrow angle glaucoma.”

How does this medication work?

Eprosartan selectively binds to the angiotensin II receptor which prevents vasoconstriction and reduces aldosterone secretion which results in a decrease in blood pressure.  Hydrochlorothiazide is a diuretic that inhibits sodium reabsorption in the distal convoluted tubule resulting in an increased excretion of sodium, potassium, hydrogen and water.

How should I take this medication?

Oral: Take Eprosartan 600mg + Hydrochlorothiazide 12.5mg once daily without regard to meals.

How to Take: May be administered without regard to meals

What should I watch for while using this medication?

Before taking Eprosartan+Hydrochlorothiazide, Teveten Plus, speak with your doctor about your medical history, especially if you have aortic/mitral stenosis, diabetes, hepatic and/or renal impairment,  hypercalcemia, hypercholesterolemia, parathyroid disease, and systemic lupus erythematosus (SLE).  Angioedema is a rare but serious adverse reaction that can occur with ACE inhibitors.  Electrolyte imbalances such as hyperkalemia may occur with angiotensin II receptor antagonists; risk factors include renal dysfunction, diabetes mellitus, and concomitant use of ACE inhibitors, aliskiren, potassium-sparing diuretics, potassium supplements, and/or potassium-containing salts. Use cautiously, if at all, with these agents and monitor potassium closely. Watch for hypotension with or without syncope; close monitoring of blood pressure is required during initial and changes in dosing.  Hydrochlorothiazide may cause acute transient myopia and acute angle-closure glaucoma.  Deterioration in renal function, particularly in those with low renal perfusion (eg. renal artery stenosis, heart failure) can occur.  Monitor glomerular filtration rate (GFR) and serum creatinine to watch for progressive deterioration in renal function.

What if I miss a dose?

If you miss a dose of medication, try to take it as soon as possible.  However, if it is almost time for your next dose, take only that scheduled dose.  Do not take double or extra doses.

How should I store this medication?

Keep out of the reach of children at all times.  Store at room temperature, 59 to 86° F (15 to 30° C).  Protect from light.  Keep the container tightly closed.  Properly dispose of any unused medication after the expiration date.

What are the possible side effects of using this medication?

Abdominal pain, diarrhea, nausea, vomiting, cystitis, hematuria, pyuria, urinary tract infection, leukocytosis, dizziness, fatigue, insomnia, asthenia, bronchitis and rhinitis.

Note this is not a complete list of side effects, only the most common.