VRAYLAR (Cariprazine)
VRAYLAR (Cariprazine)
VRAYLAR (Cariprazine)
VRAYLAR (Cariprazine)
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VRAYLAR (Cariprazine)

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$1,429.99 USD
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$1,429.99 USD
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What is this medication? 

Cariprazine, Vraylar
Second Generation (Atypical) Antipsychotic

Indicated for treatment of bipolar disorder, and schizophrenia.

Brand Name US: Vraylar
Australian Label: Reagila

ALERT: US Boxed Warning

Increased mortality in elderly patients with dementia-related psychosis:
Elderly patients with dementia-related psychosis treated with antipsychotic drugs are at an increased risk of death. Cariprazine is not approved for the treatment of patients with dementia-related psychosis.

Suicidal thoughts and behaviors:
Antidepressants increased the risk of suicidal thoughts and behavior in pediatric and young adult patients in short-term studies. Closely monitor all antidepressant-treated patients for clinical worsening and for the emergence of suicidal thoughts and behaviors.”

How does this medication work?

Cariprazine, Vraylar is a second generation atypical antipsychotic that acts as either an agonist or antagonist depending on the current concentration of central dopamine D2 and serotonin 5-HT1A neurotransmitters in the brain.  Cariprazine, Vraylar exhibits high affinity for dopamine (D2 and D3) and serotonin (5-HT1A) receptors and has low affinity for serotonin 5-HT2C and alpha 1A-adrenergic receptors.

How should I take this medication? 

Initial: Oral: Take 1.5mg once daily; adjust dose based on response and tolerability in increments of 1.5mg to 3mg.  Maximum daily dose is 6mg. 

What should I watch for while using this medication? 

Before using Cariprazine, Vraylar, speak with your doctor about your medical history, especially if you have had a stroke, suffer from diabetes, heart failure, arrhythmias, hypertension, dementia, seizures, obesity, neutropenia and swallowing problems.

What if I miss a dose?

If you miss a dose of medication, try to take it as soon as possible. However, if it is almost time for your next dose, take only that scheduled dose. Do not take double or extra doses.

How should I store this medication?

Keep out of the reach of children at all times. Store at room temperature, 59 to 86° F (15 to 30° C). Protect from light. Keep the container tightly closed. Properly dispose of any unused medication after the expiration date.

What are the possible side effects of using this medication? 

Drug-induced extrapyramidal reaction, Parkinsonian-like syndrome, akathisia, headache, insomnia, nausea, hypertension, tachycardia, drowsiness, restlessness, dizziness, anxiety, agitation, dystonia, fatigue, suicidal ideations, weight gain, hyponatremia, vomiting, constipation, abdominal pain, diarrhea, xerostomia, joint and back pain, muscle rigidity, blurred vision.

Note this is not a complete list of side effects, only the most common.